SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '792947cb0f1e4cb9292d3d3aae682b80c765f20e4fed1bc4a45aac56358a5c43' 
  AND token = 'uzB1tYcu84/J2sDjqGUb4dUJTV0rUB0i+stl9Em1640=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}