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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3eb9ae9c3f6e092e15608948f45a15fa97084f11d9ace993fdb5657d53b800' 
  AND token = 'zRoDjcGY3oRZb+Mm7Znzpo1k3hyg4zC8188dcZf3M6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}