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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf419a0351b27ca537fc8a8a7fe59d428701f54973872a8bdde82d9732f9231' 
  AND token = 'zj0tRs5u3hgvsKg2EvGG2WOSdSin2HGuGqEuSUAPXRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}