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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caa3a0099c30ad2faec46c6e005f6193101af1fbbd75c881e2422e32706079b2' 
  AND token = 'co5Ko9y0X1VaxOVcyKRqyP7kXtx03Xyridf5LsckyLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}