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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308a0da66011e3de1243fb30e4b9752124ebbb2b41630c1af61bbff4692d7b1a' 
  AND token = '8U7M1bV8BGoZ45CfEi1PA/1kexp8d39jmIsuMk2SNCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}