SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226b3538e747e68934d24cbb9811351feaf3f1a1d362deaf91caa4d954e8b08b' 
  AND token = 'zCkMaMk0Rl/izD0ehuFpmq2hz4zWANUcWh4i3ViUwWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}