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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ae8b942eb8c7d2d77929c9d65bf87046990c98dc7d6b0064a76b011285d194f' 
  AND token = 'akyIpuL4SSmpEDZykXhzHL5ECU1u3lOWicxRe5E2ebs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}