SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226843d28badcd3d7f80177c5e3ec38e73927938bbefc2307c2baf43483a1410' 
  AND token = 'p7ryNVFe/QHz+iHX4SC/FaL2s+k5zsRY1jlCcAeLlNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}