SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e57226a26f58376db14a6843e168d054d7c2fbbb80c3be05f2d8e534df7051' 
  AND token = 'b1sjLMgEwrp82NXzRbsOaLPU3GbvfTc4gu9CiS0Ox68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}