SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a51f9b670298b2a9081e8c95eebed165552c35f322ddba323043fb66c6d8d3e4' 
  AND token = 'AE9VoXjOwH4Je17MPD7FGW9eXXIwmuc0WieIJJGdcLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}