SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba97a4f73980ba831b968e0a11f1723126158493601ded412dca00fa322a0d7c' 
  AND token = 'yRX3v/un40wRvPYNhGh1A/l8jAXT+a27g0NbBtIpGrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}