SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '519083f15c0cf44ae2ed84f6f75d7223af88e3b5d7f28d67bb031f99a43751ba' 
  AND token = '2M6gLHQAmtU0cX0oNqOy6FKaYXk9rYfZHFnVoi4SXp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}