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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14442244d2ad3b274d88a375b34cf152db5d912f3b9b5dc7b86640c69384e4ac' 
  AND token = 'E3exbsKmHzlFN2EyY7EESaHVeZ0T+cWldQ3KsfqaLmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}