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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7d4162cd80265e80cbd126a220c240b61c20dc0e5df1f8100d4f3737798ffa2' 
  AND token = 'ARwR48QjB6aAtFH+fCuPF/GnaV54whDvC7MRiHTRej4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}