SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd2b9c60502cdd9ee475db3c4326300c164514c743bd86282c53602d1862786c' 
  AND token = 'CzAPzDQ3GO+yIa1I0rBpWmA4hUnj2/ZKNlHci/Xuv6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}