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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf860c07b62b262ff1166b08a6078bda41046200bb89579b340e1a9a02ac56f' 
  AND token = 'R1btO9tKX68LmzueEW9CzlxtfhVf1akaWR89ta9m/v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}