SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd6f39a825e9d68787ca2f1f3e865ba9a711c70dc2beec121b379bcdaf0c26e8' 
  AND token = 'QBx7bxvAiNRPyegC/zkx9FIZU23tZkw+UYVdpihY5nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}