SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66906de63ef4af21e122a2abaee89232c0b5255995ade16983a5126681109c27' 
  AND token = 'PoEjCT+cxk6Fx43iYYhxdPBiJSWEW9fy9gcGVEMK0NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00252

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}