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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe0e4318bcc2b3232b66ae0c7ce49c8dcb81cb6bd914b255199f206b3aee8a7e' 
  AND token = 'byJFoD7B62B3MFXAtBPs+ZZmAXK3Ef1uE8AsmTVlLTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}