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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3bd1c5da4d71023d1c6a8dbf3daaa016bb5eaa598ca57d7716d02198468a56' 
  AND token = 'afr6YxeElqzz/NDw2fro7Lj8j7GWU2WZQ4HRyqOp5iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}