SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5421ab30351479778196d1d56f012414f11af640f4cf1d07c0b8a33b2752d2' 
  AND token = 'k8LyYaEUzfeeAp2a55JXvBb6C0p7mFgDHfGEEWFzNtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}