SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1c12711d309b675425f1334099524433057adf81d130f1a7fd376a92f7a9c2' 
  AND token = 'DTS+a85ySuQbGuzJmTqUENku21tvW63sV6JpB736YnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}