SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185ae5f422f94147491507d0578e0ce8f35036f76f3a8f5d3ac020e422b493a6' 
  AND token = 'uKUroaY7Zuf8zRoH+z+fFGRVEVGdhmSDFtBVMok37fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}