SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff11425ef73a58234feb9f15d18af5d9f2606ec94ccc02af4bd2297d9269ba45' 
  AND token = 'KBoPK4q0Li8n+FE/9rrLksG3UIVgFzlQutJTnvh4TNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}