SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e43f781f78ef202178671f829d0b0119f422c67de5ee7d842a4f693d63b3616' 
  AND token = 'ynGk+nYSMC9NIB5zZ6cngrOIOCd3+Ln0iCSTK/FoBzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}