SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de25e073beeac2796e93243556b0992c84c20a2623fb78779004ad57fed2ad2b' 
  AND token = '8mek9Va5wg63yzkNu4MBj+eRULRaQcV3FrlylpQE+GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00139

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}