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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04fbd8e09db8aa0b031743dadd02fffc188ded375e437e1ffcc7b013b5552868' 
  AND token = 'XzDZGjGfjVKND4aMuriCBq10TBDBPRXlvtAPsukNeoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}