SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '610b7a434af9bd5dcbdaa6affb90089063e8395ca9da2e9212636ed70a6c4480' 
  AND token = 'JDm7q74VHq0BJvzE+Lx/OjnAcTWQbW5DKPsp17uE2aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}