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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d850c1feb7429e38185af8e134c9f2c1755b9789d6c8033b3c4d7502bb9d28' 
  AND token = 'Ro+egB7AirDtdHfch8P9S186dXNp8CaCCLko/q7huQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}