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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3191d72ca27c328185b7d2e905cc15c32e5448b44c9e75cc34d4fee75e110f7' 
  AND token = 'wRzMmqOeTbMiNBXziM85gxLhMhb2xrOzdzCTC9pVaQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}