SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5fb7bd667ef49bd03af142b89f68352a46c5ddeb155b3cf42dee40d27af0481' 
  AND token = 'o0evu4Jl2z+vmnPo44WhL5zHtNGKSTnK5QzxXPfp714=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}