SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd893f1f02e97b3a7ed7a4019cbff70aafb8cf184b1ec4c2411ede0b5a540ee' 
  AND token = 'xAMNHDjuma+k7H0ZZI8t1RBBtTAAArUE4AJFb30wiDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}