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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd623b984e4426f1fdbc3351e9fdb89e0860e959b93e1bfea5237d86ac42fa515' 
  AND token = '41qR12CD8Hqwj3U/tasBwQVn2VytthbLME1dN4XseTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}