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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0877a04a3c7c101cdc9c20d1642046251adfa0a0dba6f1dfc9c011dbdbdbf607' 
  AND token = 'EPeixC3p65b1yJ1eNheyringib4YCIdSulvIqDX8kK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}