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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a763b439b14112bf74faf7f3d3f343fcac454c6950d2c5e7dd08fe2667f2e969' 
  AND token = 'EAON5LxDrGd8RweAcM6jzTuY8X7PCbJzVTYmKAztMMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}