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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e210baf4ecf097a7d97809961c0bd95599e3a2c06c6e6ff7714b51f583c0847' 
  AND token = 'TBnIj9VJcqOZTaR5reGEOY3zucXrh2mA1PNxpw0h4xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}