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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b006cd1d00f31b44bbfcca107b0059cecf5377743db51260ec1f08ad566c51b' 
  AND token = 'Z0RdGxKCjreFkVjhApcjYmgYHAP0Nvh3H0Bg3GfUGCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}