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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e01871155602b90a8d9a837fad86e164e4846a20deed7e011df243cddc87572' 
  AND token = 'OpZsSxDII2Ny8eojzD2Um7sm7W8VAZTpu/luNi2nvpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}