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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34d69a277019333c430c8588054975ff43a68ee4940f378309126fe439f53998' 
  AND token = 'KMHoP8oJ5T7mGUrFAz5R/l6fCaESNFXt7TsSX8def4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}