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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53aaa2ede76f2bff09ec020e074e4c227c062b1d1bf456eb01962983c534b609' 
  AND token = 'HcwceS9U6rZkMrvIRmnB+9U9pUIwe2O+RwUMQwOQ8+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}