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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd113a3b22a8677aae28af6fc324d80950c43ed224b76e3f8ab83a355efbebce' 
  AND token = '6dTVfQJ1b+/e0nfLj+ZWQnhj+6o3QSE7YaK+WceQ+uI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}