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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4af10798226c022c7e053c943e847738d0620ba7e1ab7f9e102e16bd1650e8d6' 
  AND token = '7oQh8guBXwmj2ICftdzz0j0K52B3iH67kTPhBuKgWT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}