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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f44827f8fcac81fcf29ff703434942d39f8f26a62f862068e572faab7138070a' 
  AND token = 'FF3SHLP8esnrdlxkbNkecWHGQt35HdtVhxxNQ/CL4PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}