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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0a4363d8ca6ed801a19322e63fd59eeacde05c2a71a36adf865fb7b9e7333a5' 
  AND token = 'ygNm6GRSK+QpsL3mxg27d/qM5nZRaFhLxmhbVU98kLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}