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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed471fef4137ab1e03380f9c4c08d799ec26030e4b2eb9a236ae6e730d09c152' 
  AND token = 'czAC/CxrhJj64yWmw4FaD5nM7RGetLrdwRnTcbJxpZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}