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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b72ece8df3b4013bb753bc74685bf673a0e4b0fee3e3338e450326ed1abdfba' 
  AND token = 't4hQRb4Ak3AdaXGhYCuUlN7+bacQdB9v9CPlSTJX1TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}