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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286931a5044a423d03c3f5a4afab6bd78668e5f1b749e9fdd38de4590fa2bc90' 
  AND token = 'tjnJ6T9Dd4snyNhEwssRI8QXBSPQ4t0o8Y5wXq6pELM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}