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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd854179c1086b5855b364e2c6f362218e34e2ef3d48428cb9414e82f69aaed6' 
  AND token = 'RIBvQOsEolqqoi1XG14KTN1uj3xua8iBO4yPVeH47qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}