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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8195f5d33098bd7144efe45d2adbfc5f221244315ee4d6132596835455daeb' 
  AND token = 'UepRTj/Lt2MxgOCTErkqhC262tb3TeoX0P6ykjhem44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}