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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be84a24610f92e3ec364066486cb49d9141341feec783d085826e40c18ef0247' 
  AND token = 'GTRHPoPWpPeXB+t4AliWbja1HnIfVvf4o6hX5cgi7xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}